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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DLC1
All Species:
5.15
Human Site:
S586
Identified Species:
14.17
UniProt:
Q96QB1
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96QB1
NP_006085.2
1528
170592
S586
G
G
T
L
M
D
L
S
E
R
Q
E
V
S
S
Chimpanzee
Pan troglodytes
XP_001138622
1528
170386
S586
G
G
T
L
M
D
L
S
E
R
Q
E
V
S
S
Rhesus Macaque
Macaca mulatta
XP_001091659
1528
170709
G586
G
G
T
L
M
D
R
G
E
R
Q
E
V
S
S
Dog
Lupus familis
XP_849359
1004
111320
P124
L
V
G
S
G
G
P
P
S
P
R
D
A
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0Z9
1092
123349
S212
P
S
P
K
E
L
S
S
F
S
F
S
M
K
G
Rat
Rattus norvegicus
Q63744
1091
123396
L210
S
L
P
S
P
K
E
L
S
S
F
S
F
S
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511069
1089
120124
P209
E
A
S
D
R
G
G
P
D
S
A
G
G
T
P
Chicken
Gallus gallus
XP_420693
1575
176028
D629
S
R
E
S
V
L
T
D
L
S
E
R
Q
E
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001921774
1100
122120
A220
C
S
S
G
T
S
G
A
N
E
D
S
M
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
97.3
38.6
N.A.
66.2
66.3
N.A.
38.9
72.8
N.A.
41.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.3
98.4
50
N.A.
68
68.1
N.A.
51.1
81.9
N.A.
53
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
86.6
0
N.A.
6.6
6.6
N.A.
0
0
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
86.6
13.3
N.A.
13.3
6.6
N.A.
20
13.3
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
0
0
0
0
12
0
0
12
0
12
0
0
% A
% Cys:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
12
0
34
0
12
12
0
12
12
0
0
12
% D
% Glu:
12
0
12
0
12
0
12
0
34
12
12
34
0
12
0
% E
% Phe:
0
0
0
0
0
0
0
0
12
0
23
0
12
0
0
% F
% Gly:
34
34
12
12
12
23
23
12
0
0
0
12
12
0
23
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
12
0
12
0
0
0
0
0
0
0
12
0
% K
% Leu:
12
12
0
34
0
23
23
12
12
0
0
0
0
12
0
% L
% Met:
0
0
0
0
34
0
0
0
0
0
0
0
23
0
12
% M
% Asn:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% N
% Pro:
12
0
23
0
12
0
12
23
0
12
0
0
0
0
12
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
34
0
12
0
0
% Q
% Arg:
0
12
0
0
12
0
12
0
0
34
12
12
0
0
0
% R
% Ser:
23
23
23
34
0
12
12
34
23
45
0
34
0
56
34
% S
% Thr:
0
0
34
0
12
0
12
0
0
0
0
0
0
12
0
% T
% Val:
0
12
0
0
12
0
0
0
0
0
0
0
34
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _